A-Fantrine 40mg injection 10 Ampx1ml

Product Overview

Product Form: Injection
Package Quantity: 10 Ampoules x 1ml
Manufacturer: Atco
Prescription Requirement: Yes

Description

A-Fantrine 40mg Injection is a highly effective treatment for severe malaria, particularly in cases of cerebral malaria or chloroquine-resistant Plasmodium falciparum. The active ingredient, Artemether, is a potent antimalarial agent that works by disrupting the malaria parasite's lifecycle in the body. A-Fantrine is administered intravenously, providing rapid relief in critical cases, and is often used when other treatments are not effective. It is designed for use under medical supervision due to the intensity of the conditions it treats.

Functions

A-Fantrine works by inhibiting the growth and replication of the malaria parasite, Plasmodium falciparum, within the body. Artemether, the primary active component, targets the parasite's mitochondria and disrupts its cellular function, leading to the parasite’s death. This helps in reducing the intensity of the infection, particularly in severe cases like cerebral malaria, which can affect the brain, or in cases where the malaria strain is resistant to chloroquine.

Precautions

A-Fantrine should be used with caution in patients who have electrolyte disturbances or those taking medications that prolong the QT interval (a heart condition that causes irregular heartbeats). It is crucial to monitor patients for any signs of dizziness or heart-related side effects during treatment. The drug should not be used in conjunction with certain drugs, such as antiarrhythmic medications or antidepressants, as these may interact negatively with Artemether. Patients with severe kidney or heart conditions should inform their doctor before starting treatment.

Side Effects

Common side effects of A-Fantrine include abdominal pain, nausea, vomiting, and dizziness. Some patients may experience anorexia (loss of appetite) or diarrhea. These side effects are typically short-term but should be monitored. In rare cases, patients may experience more severe reactions such as heart irregularities, which require immediate medical attention. If side effects persist or worsen, it is essential to seek medical advice promptly.

Cautions

A-Fantrine is contraindicated in pregnant and breastfeeding women due to the lack of sufficient safety data regarding its effects on both the mother and the baby. It is also not suitable for individuals with a history of arrhythmias (abnormal heart rhythms), bradycardia (slow heart rate), or congestive heart failure. Extra care should be taken if you are using other drugs that can affect the heart or electrolyte balance. Always consult a healthcare provider before starting treatment to ensure that A-Fantrine is the right choice for your condition.