Amphonex 50mg Injection

Product Description

Amphonex Injection 50mg is a liposomal formulation of Amphotericin B used to treat severe and potentially life-threatening fungal infections. It is designed to be less toxic to the kidneys than conventional Amphotericin B, while maintaining strong antifungal activity. This medicine is administered intravenously under strict hospital supervision.

Product Overview

Product Name: Amphonex Injection 50mg
Form: Injection
Pack Size: 1’s
Manufactured By: BSV Limited
Used For: Treatment of severe systemic and invasive fungal infections
Prescription Required: Yes

Ingredients & How They Work

Liposomal Amphotericin B:
Amphonex contains Amphotericin B in a liposomal formulation, which helps deliver the drug directly to infected tissues while reducing toxicity to healthy organs. It binds to fungal cell membranes, creating pores that cause cell death, making it highly effective for serious fungal infections such as candidiasis, aspergillosis, cryptococcosis, and fungal meningitis.

Key Benefits

Effective against a wide range of severe fungal infections
Lower risk of kidney toxicity compared to conventional Amphotericin B
Suitable for immunocompromised patients
Beneficial for invasive infections affecting major organs
Useful in treating fungal meningitis and systemic mycoses

How to Use

Administered intravenously in a hospital setting
Dose and infusion rate determined by the treating physician
Patients are monitored for infusion-related reactions
Hydration may be recommended before and during treatment
Regular kidney and liver function tests are required
Follow medical advice strictly throughout therapy

Side Effects & Precautions

Common Side Effects

Fever, chills, or rigors during infusion
Nausea or vomiting
Abdominal pain
Headache
Fatigue
Electrolyte imbalances such as low potassium or magnesium
Elevated liver enzymes
Anemia or low red blood cell count

Serious Side Effects

Kidney dysfunction (though less severe than conventional forms)
Severe allergic reactions including rash or breathing difficulty
Infusion-related reactions

Precautions

Monitor kidney and electrolyte levels regularly
Administer only in a hospital where monitoring is available
Use cautiously in patients with kidney or liver disease
Adequate hydration may reduce kidney-related side effects
Avoid use during pregnancy unless clearly necessary
Avoid combining with other nephrotoxic medications
Monitor closely for infusion reactions, although these are typically milder with liposomal formulations

Who Should Use

Patients with severe systemic or invasive fungal infections
Individuals with weakened immune systems such as HIV/AIDS or chemotherapy patients
Patients requiring treatment for fungal infections of the brain, lungs, kidneys, or bloodstream

Storage Instructions

Store in a cool, dry place
Keep away from direct sunlight
Do not freeze
Keep out of reach of children

Disclaimer

This medication must be used strictly under medical supervision. It is not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before use, especially if you have underlying health conditions or are taking other medications.