Avastin Infusion 400mg/16ml

Product Description

Avastin Infusion 400mg/16ml contains bevacizumab, a monoclonal antibody used to treat various types of cancer. It works by inhibiting vascular endothelial growth factor (VEGF), a substance that promotes the growth of blood vessels that supply tumors. By blocking VEGF, Avastin slows the development of new blood vessels, helping to restrict tumor growth and spread. This infusion is administered under strict medical supervision in a hospital or clinical setting.

Product Overview

Product Name: Avastin Infusion 400mg/16ml
Form: Infusion
Pack Size: 16ml
Manufactured By: Roche Pakistan
Used For: Treatment of multiple cancers including colorectal, lung, kidney, ovarian, cervical cancers, and glioblastoma
Prescription Required: Yes

Ingredients & How They Work

Bevacizumab:
Avastin contains bevacizumab, a recombinant humanized monoclonal antibody. It targets and blocks VEGF, preventing the formation of new blood vessels that tumors need to grow. By inhibiting angiogenesis, bevacizumab helps slow tumor progression and enhances the effectiveness of chemotherapy when used in combination.

Key Benefits

Inhibits tumor blood supply
Effective for various advanced or metastatic cancers
Often used in combination with chemotherapy
Helps slow tumor growth and spread
May improve overall survival in several cancer types

How to Use

Administered intravenously under medical supervision
Infused slowly to reduce the risk of reactions
Dosage and frequency depend on the type of cancer being treated
Patients are monitored during and after infusion
Blood pressure checks and urine tests may be required regularly
Follow all medical instructions provided by the healthcare team

Side Effects & Precautions

Common Side Effects

Hypertension
Fatigue
Diarrhea
Nausea
Decreased appetite
Headache
Mouth sores
Proteinuria

Serious Side Effects

Bleeding complications including gastrointestinal bleeding
Gastrointestinal perforation
Delayed wound healing
Blood clots such as stroke or pulmonary embolism
Heart problems including heart failure

Precautions

Control pre-existing hypertension before starting treatment
Avoid use in patients with recent surgery or unhealed wounds due to delayed wound healing
Monitor closely if there is a history of bleeding disorders
Not recommended during pregnancy or breastfeeding due to potential fetal risk
Inform your doctor of any heart or vascular conditions
Report any unusual bleeding, severe abdominal pain, or sudden shortness of breath immediately

Who Should Use

Patients diagnosed with advanced or metastatic cancers such as colorectal cancer, lung cancer, renal cell carcinoma, ovarian cancer, cervical cancer, or glioblastoma
Individuals receiving combination therapy with chemotherapy for improved effectiveness

Storage Instructions

Store in a refrigerator between 2°C and 8°C
Do not freeze
Protect from light
Keep out of reach of children

Disclaimer

This medication must be used only under the supervision of qualified healthcare professionals. It is not intended to diagnose, treat, cure, or prevent any disease. Consult your doctor before use, especially if you have underlying health conditions or are taking other medications.