Tasmi-Am Tablets 5mg + 40mg is a combination medication containing two active ingredients: Telmisartan (40mg) and Amlodipine (5mg). Telmisartan belongs to the class of angiotensin II receptor antagonists that helps relax blood vessels, improving blood flow and reducing high blood pressure. Amlodipine is a calcium channel blocker that also aids in the relaxation of blood vessels, effectively lowering blood pressure and reducing the workload on the heart. Together, these medications work to manage hypertension and help prevent complications such as heart attacks and strokes.
Purpose
Tasmi-Am Tablets are primarily used for the treatment of:
Hypertension (High Blood Pressure): The combination of Telmisartan and Amlodipine works synergistically to control high blood pressure, lowering the risk of cardiovascular events such as heart attacks and strokes.
Prevention of Heart-Related Conditions: By effectively managing blood pressure, this medication also helps reduce strain on the heart and blood vessels, promoting long-term heart health.
Warnings
Hypotension Risk: Patients with a sensitive renin-angiotensin system, such as those who are salt- or volume-depleted, may experience symptomatic low blood pressure (hypotension) upon initiation of treatment.
Severe Aortic Stenosis: Caution should be taken when administering Amlodipine in patients with severe aortic stenosis, as it may cause acute low blood pressure.
Liver Function: Patients with liver insufficiency or biliary obstructive disorders should be closely monitored when using this medication, as Telmisartan is metabolized in the liver.
Kidney Transplant: Regular monitoring of potassium and creatinine levels is advised for patients who have recently undergone a kidney transplant, as the medication is not dialyzable.
Adverse Effects
Common side effects of Tasmi-Am Tablets include:
Telmisartan-related Side Effects: Increased sweating, dizziness, leg pain, insomnia, dry mouth, constipation, abnormal ECG, and more.
Amlodipine-related Side Effects: Dizziness, arrhythmia, peripheral edema, bradycardia, diarrhea, nausea, flatulence, gingival hyperplasia, and others.
Serious but rare side effects:
Hypotension
Severe allergic reactions
Changes in heart rhythm (tachycardia or bradycardia)
Muscle weakness
Vision changes
Seek immediate medical attention if serious side effects or allergic reactions occur.
Cautions
Drug Interactions: Tasmi-Am Tablets may interact with several medications, including Baclofen, potassium-sparing diuretics, lithium, and CYP3A4 inhibitors (such as erythromycin and diltiazem). Ensure your doctor is informed about all the medications you are taking.
Alcohol: Limit alcohol consumption, as it may amplify side effects such as dizziness or fainting.
Driving and Operating Machinery: Since dizziness and drowsiness are possible side effects, avoid tasks requiring full alertness, such as driving, until you know how this medication affects you.
Pregnancy and Breastfeeding: Consult your healthcare provider before using Tasmi-Am Tablets during pregnancy or while breastfeeding. It is important to follow your doctor’s advice closely.
Storage
Store Tasmi-Am Tablets at room temperature, away from direct sunlight and moisture. Keep out of reach of children and ensure that the medication is stored in its original packaging to maintain its effectiveness.
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