Jakafi Tablets 10mg

Product Description

Jakafi Tablets 10mg contain ruxolitinib, a Janus kinase (JAK) inhibitor used to treat certain blood disorders by targeting abnormal signaling pathways in the bone marrow and immune system.

Product Overview

Product Name: Jakafi Tablets 10mg
Product Form: Tablets
Pack Size: 60's
Manufactured By: Indus Pharma
Used For: Treatment of myelofibrosis, polycythemia vera, and graft-versus-host disease
Prescription Required: Yes

How It Works

Ruxolitinib works by inhibiting the activity of JAK enzymes, which are involved in the signaling pathways that control blood cell production and immune responses. By targeting these pathways, Jakafi helps reduce abnormal blood cell growth, inflammation, and immune overactivity.

Key Benefits

Treats intermediate or high-risk myelofibrosis by managing abnormal blood cell production
Provides therapy for polycythemia vera in patients intolerant or unresponsive to hydroxyurea
Manages steroid-refractory acute and chronic graft-versus-host disease in adults and pediatric patients 12 years and older
Reduces symptoms such as fatigue, splenomegaly, and inflammation associated with blood disorders

How to Use

Take Jakafi Tablets exactly as prescribed by your doctor
Swallow the tablet whole with water, usually twice daily, or as instructed by your healthcare provider
Regular monitoring of blood counts and liver function is essential during treatment

Side Effects and Precautions

Common Side Effects

Reduced platelet count (thrombocytopenia), increasing bleeding risk
Anemia, leading to fatigue and weakness
Reduced white blood cell count (neutropenia), increasing infection risk
Bruising and bleeding due to low platelet counts
Headache and dizziness
Elevated cholesterol levels
Weight gain
Reactivation of herpes zoster virus (shingles)
Elevated liver enzymes

Precautions

Regular blood monitoring to track anemia, thrombocytopenia, and neutropenia
Report any signs of infection promptly due to reduced immunity
Dose adjustments may be required in patients with liver or kidney impairment
Monitor for arrhythmias in patients with a history of heart disease
Not recommended during pregnancy or breastfeeding
Inform your healthcare provider about all other medications to avoid drug interactions

Who Should Use

Patients diagnosed with myelofibrosis, polycythemia vera, or graft-versus-host disease under specialist supervision

Storage Instructions

Store in a cool, dry place away from direct sunlight
Keep out of reach of children and use before the expiry date

Disclaimer

This medication must be used under medical supervision. The information provided does not replace professional medical advice. Always consult your doctor for diagnosis, treatment planning, and correct dosing instructions