Mirtazep Tablets 30mg

Product overview:

Product form: Tablets 

Pack size: 20

Manufactured by: ZAFA PHARMACEUTICAL LABORATORIES (PVT) LTD

Prescription: Yes

Product Details

Mirtazep Tablets 30mg contain the active ingredient mirtazapine, a central presynaptic alpha-2 antagonist. This medication enhances noradrenergic and serotonergic neurotransmission by specifically increasing serotonergic activity through 5-HT1 receptors while blocking 5-HT2 and 5-HT3 receptors. The histamine H1-antagonistic properties of Mirtazep contribute to its sedative effects, helping with the regulation of mood and anxiety.

Purposes

Mirtazep Tablets 30mg are primarily indicated for:

• Major Depressive Episodes: Effective in treating episodes of major depression in adults, helping to improve mood and alleviate symptoms associated with depression.

Warnings

Mirtazep requires careful monitoring due to potential risks. Patients should be closely observed for any signs of suicidal behavior, as these may arise during treatment. Additionally, rare but serious conditions such as bone marrow depression, which can present as granulocytopenia or agranulocytosis, may occur. If jaundice develops, treatment with Mirtazep should be discontinued immediately.

Adverse Effects

Common side effects of Mirtazep Tablets 30mg include:

• Sedation and Drowsiness: Due to its histamine H1-antagonistic activity.
• Weight Gain and Increased Appetite: Notable changes in weight and eating patterns.
• Neuropsychiatric Effects: Such as abnormal dreams, confusion, agitation, and suicidal thoughts.
• Physical Symptoms: Including dizziness, headache, tremor, and paraesthesia.

Less common but serious side effects might include bone marrow suppression and serotonin syndrome.

Cautions

Mirtazep is not recommended for children and adolescents under 18 years due to the risk of suicidal thoughts and hostility. Regular monitoring is crucial to manage any emerging symptoms of suicidal ideation or severe mood changes. Additionally, Mirtazep should be used with caution if there are signs of jaundice or if there is a history of bone marrow issues.

Always consult a healthcare provider before starting Mirtazep Tablets 30mg to ensure it is appropriate for your condition and to receive guidance on monitoring and managing potential side effects.