Ranola Tablets 500Mg

Product Overview

Product Form: Tablets
Pack Size: 500 mg
Manufactured By: HIGHNOON LABORATORIES LTD
Prescription Required: Yes

Product Details

Ranola Tablets 500 mg contain Ranolazine, a medication used primarily for managing chronic angina. The exact mechanism of action of Ranola is not fully understood, but it is believed to exert its effects by inhibiting the late sodium current in cardiac cells. This inhibition reduces intracellular sodium and calcium overload, which can improve myocardial relaxation and decrease left ventricular diastolic stiffness. Clinical studies have demonstrated that Ranola can significantly shorten the QTc interval and enhance diastolic relaxation in patients with certain genetic conditions.

Purposes

Ranola Tablets are indicated for the treatment of chronic angina. By mitigating intracellular ionic imbalances and enhancing myocardial relaxation, Ranola helps to alleviate the symptoms associated with chronic angina, thus improving patients' quality of life. It is used as part of a comprehensive management plan for individuals suffering from chronic angina to help manage their condition effectively.

Warnings

1. Combination Factors: In patients with multiple risk factors, such as mild hepatic or renal impairment, elderly patients, or those with low body weight, Ranola should be used with caution. Increased exposure may lead to dose-dependent side effects, requiring frequent monitoring, possible dose adjustments, and discontinuation if necessary.

2. CYP3A4 Inducers: Ranola should not be used in combination with CYP3A4 inducers (e.g., rifampicin, phenytoin, or carbamazepine), as this may reduce the medication's efficacy.

3. QT Interval Prolongation: Caution is advised when treating patients with a history of long QT syndrome or those on medications affecting the QTc interval. Regular monitoring is recommended to prevent adverse effects related to QT prolongation.

Adverse Effects

Common side effects of Tablets 500 mg include dizziness, headache, and gastrointestinal issues such as nausea. Less common effects might involve visual disturbances, tinnitus, and postural hypotension. Rare but serious side effects include severe allergic reactions, hallucinations, and significant alterations in consciousness. Seek medical advice if severe symptoms occur.

Cautions

Patients using Ranola should be cautious if they have mild to moderate renal or hepatic impairment, or if they are elderly, have low body weight, or suffer from moderate to severe congestive heart failure (CHF). The medication should not be used in patients with severe kidney or liver issues or in combination with certain antibiotics, antifungals, or medications for heart rhythm disorders without medical supervision. Always consult your physician before starting Ranola to ensure it is suitable for your condition and to discuss any potential risks. Store the tablets at room temperature, away from direct light and heat.