Vonozan Tablets 10mg contain Vonoprazan, a potassium competitive acid blocker (P-CAB). Unlike traditional proton pump inhibitors, Vonozan Tablets do not need activation by acid. Instead, they work by reversibly and competitively inhibiting H+, K+-ATPase, thereby significantly reducing gastric acid production. Due to its high basicity and long-lasting effect on gastric parietal cells, Vonozan effectively prevents mucosal damage in the upper gastrointestinal tract.
Purposes
Vonozan Tablets 10mg are used to manage and treat:
Gastric Ulcers: Provides relief from the pain and discomfort caused by gastric ulcers.
Duodenal Ulcers: Aids in the healing of ulcers located in the duodenum.
Reflux Esophagitis: Helps treat inflammation of the esophagus caused by acid reflux.
Prevention of Ulcer Recurrence: Prevents the recurrence of ulcers during low-dose aspirin or NSAID administration.
Warnings
Reflux Esophagitis Management: Use Vonozan Tablets for maintaining healing only in patients with recurrent conditions. Avoid long-term maintenance if not necessary.
Long-Term Use: If healing is achieved and there is no risk of recurrence, consider reducing the dose from 20mg to 10mg or discontinuing the medication.
Renal Disorders: Exercise caution when administering Vonozan Tablets to patients with renal issues, as delayed excretion can lead to increased blood concentrations of the drug.
Adverse Effects
Common side effects of Vonozan Tablets 10mg may include:
Gastrointestinal Issues: Diarrhea, constipation, abdominal distension, and nausea.
Systemic Reactions: Drug hypersensitivity, including anaphylactic shock and eosinophilia.
Cautions
Monitoring: Regular monitoring is advised to assess the necessity of continued therapy and adjust dosage as needed.
Drug Interactions: Be cautious with drugs affecting CYP3A4, including certain antibiotics and antifungals, as they may interact with Vonozan Tablets.
Hypersensitivity: Do not use if there is a known hypersensitivity to Vonoprazan or its components.
Vonozan Tablets 10mg offer a potent solution for managing acidity and ulcers, but it is essential to follow medical advice and monitor for potential side effects. Always consult with your healthcare provider before starting or adjusting treatment.
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