Vonozan Tablets 20mg contain Vonoprazan, a potent potassium competitive acid blocker (P-CAB) designed to provide effective relief from acidity and ulcers. Unlike traditional acid blockers, Vonozan Tablets work by directly inhibiting the H+, K+-ATPase enzyme in a reversible and potassium-competitive manner. This unique mechanism allows Vonozan to significantly reduce gastric acid production, making it highly effective for managing mucosal damage in the upper gastrointestinal tract.
Purposes
Vonozan Tablets 20mg are indicated for the treatment of various gastrointestinal conditions, including gastric ulcers, duodenal ulcers, and reflux esophagitis. They are also used to prevent the recurrence of gastric or duodenal ulcers during low-dose aspirin or NSAID administration. By controlling stomach acid production, Vonozan helps in reducing symptoms and promoting healing in the gastrointestinal tract.
Warnings
Vonozan Tablets should be administered with caution in patients who require long-term maintenance therapy for reflux esophagitis. It is advisable to consider dose reduction or discontinuation if there is no risk of recurrence. Additionally, careful monitoring is required for patients with renal disorders, as delayed excretion of Vonozan may lead to increased blood levels of the drug.
Adverse Effects
Common side effects of Vonozan Tablets 20mg include diarrhea, constipation, and nausea. Some patients may experience drug hypersensitivity reactions, such as rash or urticaria. Rare but serious adverse effects include hepatotoxicity, jaundice, and elevated liver enzymes. Regular monitoring of liver function is recommended during treatment with Vonozan.
Cautions
Before starting Vonozan Tablets, consult your physician if you have a known hypersensitivity to Vonoprazan or any of its components. Vonozan should be used with caution in patients receiving specific medications like atazanavir or rilpivirine hydrochloride, as these can interact with the drug. Ensure close monitoring of the treatment course to adjust the dosage as needed based on individual disease conditions and response.
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