Aztinam Injection 1g

Product Description

Aztinam Injection 1g contains aztreonam, a monobactam antibiotic used to treat a variety of serious infections caused by Gram-negative bacteria. It is commonly administered in hospital settings and is effective for respiratory, urinary, abdominal, skin, and bloodstream infections. The injection works by inhibiting bacterial cell wall synthesis, ultimately leading to the death of the bacteria.

Product Overview

Product Name: Aztinam Injection 1g
Form: Injection
Pack Size: 1's
Manufactured By: Gland Pharma
Used For: Treatment of Gram-negative bacterial infections
Prescription Required: Yes

Ingredients & How They Work

Aztreonam:
Aztinam contains aztreonam, a monobactam antibiotic that targets Gram-negative bacteria. It binds to bacterial cell wall–producing enzymes, preventing proper cell wall formation and causing bacterial death. It is especially valuable for patients with suspected Pseudomonas infections and those with beta-lactam allergies, since cross-reactivity with penicillins and cephalosporins is rare.

Key Benefits

Effective against a wide range of Gram-negative bacteria
Useful for severe infections including pneumonia, UTIs, sepsis, and abdominal infections
Lower risk of allergic cross-reaction in patients with penicillin or cephalosporin allergies
Can be used for Pseudomonas infections
Suitable for hospital-acquired and complicated infections

How to Use

Administered intravenously or intramuscularly by healthcare professionals
Dosage depends on infection severity and patient condition
Dosage adjustments may be required for patients with renal impairment
Complete the full course as directed by the physician
Patients may be monitored for allergic reactions and liver or kidney function during therapy

Side Effects & Precautions

Common Side Effects

Diarrhea
Rash
Nausea
Vomiting
Pain, redness, or swelling at the injection site
Elevated liver enzymes

Serious Side Effects

Severe allergic reactions
Clostridioides difficile-associated diarrhea
Low white blood cell count (neutropenia)
Liver damage

Precautions

Use caution in individuals with severe beta-lactam allergies, even though cross-reactivity is rare
Adjust dosage in patients with kidney impairment
Use during pregnancy only if clearly needed
Consult a doctor before using while breastfeeding, as aztreonam may pass into breast milk
Prolonged use may lead to superinfections such as fungal overgrowth or resistant bacteria

Who Should Use

Patients with confirmed or suspected Gram-negative bacterial infections
Individuals requiring treatment for pneumonia, UTIs, sepsis, skin, or abdominal infections
Patients with Pseudomonas aeruginosa infections
Those who require an alternative antibiotic due to beta-lactam allergies

Storage Instructions

Store in a cool, dry place
Protect from direct sunlight
Keep out of reach of children
Reconstituted solution should be used promptly or stored as per healthcare guidance

Disclaimer

This medication must be used under the supervision of qualified healthcare professionals. It is not intended to diagnose, treat, cure, or prevent any disease. Always consult your doctor before use, especially if you have underlying medical conditions or are taking other medications.