Rancard-Xr Tablets 500Mg

Product Overview

Product Form: Tablets
Pack Size: 500 mg
Manufactured By: SEARLE PAKISTAN

Prescription Required: Yes

Product Details

Tablets 500 mg contain Ranolazine, a medication used to manage chronic angina. While the exact mechanism of action of Rancard-Xr is not fully understood, it is believed to reduce intracellular sodium and calcium overload by inhibiting the late sodium current in cardiac cells. This action helps alleviate angina by improving myocardial relaxation and reducing left ventricular diastolic stiffness. Clinical evidence suggests that Rancard-Xr can significantly shorten the QTc interval and improve diastolic relaxation in specific cases, such as those with long QT syndrome.

Purposes

Rancard-Xr Tablets are indicated for the treatment of chronic angina. By addressing intracellular ionic imbalances during ischemic episodes, Rancard-Xr helps to relieve symptoms associated with chronic angina, thus enhancing the patient's quality of life. It works to improve heart function and manage the symptoms of angina effectively.

Warnings

1. Factor Combinations: Rancard-Xr should be used with caution in patients who have multiple risk factors such as mild hepatic or renal impairment, elderly individuals, or those with low body weight. Increased exposure to the medication may lead to dose-dependent side effects, necessitating frequent monitoring and potential dose adjustments.

2. CYP3A4 Inducers: Avoid using Rancard-Xr in combination with CYP3A4 inducers like rifampicin, phenytoin, or carbamazepine, as this may reduce the medication's effectiveness.

3. QT Interval Prolongation: Use Rancard-Xr cautiously in patients with a history of long QT syndrome or those who are on drugs affecting the QTc interval. Regular monitoring is advised to prevent adverse effects related to QT prolongation.

Adverse Effects

Common side effects of  Tablets 500 mg include dizziness, headache, and gastrointestinal disturbances such as nausea. Less common effects might involve visual disturbances, tinnitus, and orthostatic hypotension. Rare but serious side effects can include severe allergic reactions, hallucinations, and significant changes in consciousness. Consult a healthcare provider if severe symptoms occur.

Cautions

When taking Rancard-Xr, patients should be cautious if they have mild to moderate renal or hepatic impairment, are elderly, have low body weight, or suffer from moderate to severe congestive heart failure (CHF). The medication should not be used with certain antibiotics, antifungals, or medications for heart rhythm disorders without proper medical supervision. Always consult your physician before starting Rancard-Xr to ensure it is appropriate for your condition. Store the tablets at room temperature, away from direct light and heat.